In this webinar organized by the RWE4Decisions multi-stakeholder initiative, consideration will be given to methodological recommendations on generation and use of real-world evidence (RWE) in pricing and reimbursement decision-making with a view to identifying what steps need to be taken to align on the way forwards. Guidance can act as a roadmap to generate high-quality RWE, to enable researchers and manufacturers to have a clear understanding of how it will be evaluated and for decision-makers to assess the completeness of their own RWE guidance.